BDBM452774 6-((3-((1R,5S,6r)-3- (3-fluorophenyl)-3- azabicyclo[3.1.0] hexan-6-yl)-1,2,4- oxadiazol-5-yl) methyl)pyrido[2,3-d] pyridazin-5(6H)-one::US10711004, Example 96

SMILES Fc1cccc(c1)N1C[C@H]2[C@@H](C1)[C@@H]2c1noc(Cn2ncc3ncccc3c2=O)n1

InChI Key InChIKey=RTOPZEJDITVXGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452774   

LigandPNGBDBM452774(6-((3-((1R,5S,6r)-3- (3-fluorophenyl)-3- azabicycl...)
Affinity DataIC50: 8.39nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452774(6-((3-((1R,5S,6r)-3- (3-fluorophenyl)-3- azabicycl...)
Affinity DataIC50: 5.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent