BDBM452772 1-((3-((1R,5R,6S)-3- (3,4-difluorophenyl) bicyclo[3.1.0]hex-2- en-6-yl)-1,2,4- oxadiazol-5-yl) methyl)-7-methyl- 1,7-dihydro-6H-::US10711004, Example 94

SMILES Cn1cnc2ncn(Cc3nc(no3)[C@H]3[C@@H]4CC(=C[C@H]34)c3ccc(F)c(F)c3)c(=O)c12

InChI Key InChIKey=SJUCKSBEIQPXBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452772   

LigandPNGBDBM452772(1-((3-((1R,5R,6S)-3- (3,4-difluorophenyl) bicyclo[...)
Affinity DataIC50: 9.35nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452772(1-((3-((1R,5R,6S)-3- (3,4-difluorophenyl) bicyclo[...)
Affinity DataIC50: 4.90nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent