BDBM451734 6-(2-amino-5- (benzo[d]thiazol-6-yl)pyridin- 3-yl)-3,4-dihydroisoquinolin- 1(2H)-one::US10710978, Compound I-44

SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1ccc2ncsc2c1

InChI Key InChIKey=FKUYMJCSXBTRJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 451734   

TargetSerine/threonine-protein kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM451734(6-(2-amino-5- (benzo[d]thiazol-6-yl)pyridin- 3-yl)...)
Affinity DataIC50: 120nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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