BDBM451421 US10709719, Example 668

SMILES CCCCS(=O)N[C@@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1

InChI Key InChIKey=HZKHPCQKDCTMTB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 451421   

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM451421(US10709719, Example 668)
Affinity DataIC50: 10nMAssay Description:GTPγS:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM451421(US10709719, Example 668)
Affinity DataIC50: 10nMAssay Description:GTPγS:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM451421(US10709719, Example 668)
Affinity DataIC50: 1.00E+4nMAssay Description:GTPγS:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 μl/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent