BDBM4512 4-Phenylamino-3-quinolinecarbonitrile deriv. 2q::4-[(3,4-Dichlorophenyl)amino]-6,7-dimethoxy-3-quinolinecarbonitrile::4-[(3,4-dichlorophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile

SMILES COc1cc2ncc(C#N)c(Nc3ccc(Cl)c(Cl)c3)c2cc1OC

InChI Key InChIKey=OHWOGIKXDCWJAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4512   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4512(4-[(3,4-Dichlorophenyl)amino]-6,7-dimethoxy-3-quin...)
Affinity DataIC50: 57nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed