BDBM4510 4-Phenylamino-3-quinolinecarbonitrile deriv. 2o::4-[(2,6-Dichlorophenyl)amino]-6,7-dimethoxy-3-quinolinecarbonitrile::4-[(2,6-dichlorophenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile

SMILES COc1cc2ncc(C#N)c(Nc3c(Cl)cccc3Cl)c2cc1OC

InChI Key InChIKey=COFRAMCFSKKMGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4510   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4510(4-[(2,6-dichlorophenyl)amino]-6,7-dimethoxyquinoli...)
Affinity DataIC50: 61nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed