BDBM450606 N-[(3-Chloro-4-cyanophenyl)methyl]-2-[6-[1-(3-methoxypropanoyl)piperidin-4-yl]-4-oxopyrido[3,4-d]pyrimidin-3-yl]-N-methylacetamide::US10676446, Example 190

SMILES COCCC(=O)N1CCC(CC1)c1cc2c(cn1)ncn(CC(=O)N(C)Cc1ccc(C#N)c(Cl)c1)c2=O

InChI Key InChIKey=RJNVPAWFMFFJQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450606   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM450606(US10676446, Example 190 | N-[(3-Chloro-4-cyanophen...)
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
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Date in BDB:
3/10/2021
Entry Details
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