BDBM450602 US10676446, Example 186::[2-[4-[3-[2-[(3-Chloro-4-cyanophenyl)methyl-methylamino]-2-oxoethyl]-4-oxoquinazolin-6-yl]piperidin-1-yl]-2-oxoethyl]nitrate

SMILES CN(Cc1ccc(C#N)c(Cl)c1)C(=O)Cn1cnc2ccc(cc2c1=O)C1CCN(CC1)C(=O)CO[N+]([O-])=O

InChI Key InChIKey=KEBQMKOQADRWHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450602   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM450602(US10676446, Example 186 | [2-[4-[3-[2-[(3-Chloro-4...)
Affinity DataIC50: 4nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
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Date in BDB:
3/10/2021
Entry Details
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