BDBM450539 2-[6-[1-(9H- Fluoren-9- ylmethoxycarbonyl)- 4-piperidyl]-4- oxoquinazolin-3- yl]acetic acid (intermediate A-8) and 1-(3,4- dichlorophenyl)-N- methylmethanamine ([CAS RN 5635-67-6])::US10676446, Example 124

SMILES CN(Cc1ccc(Cl)c(Cl)c1)C(=O)Cn1cnc2ccc(cc2c1=O)C1CCN(CC1)C(C)=O

InChI Key InChIKey=XUTBXGJGPRFREN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450539   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM450539(US10676446, Example 124 | 2-[6-[1-(9H- Fluoren-9- ...)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
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Date in BDB:
3/10/2021
Entry Details
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