BDBM450382 1-[4-(1-amino-2,2,2-trifluoroethyl)-2,6-dichlorophenyl]-3-{[6-(trifluoromethyl)-3-pyridinyl]methyl}urea::US10676438, Example 79

SMILES NC(c1cc(Cl)c(NC(=O)NCc2ccc(nc2)C(F)(F)F)c(Cl)c1)C(F)(F)F

InChI Key InChIKey=WYRSKUBUFKBAFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450382   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM450382(US10676438, Example 79 | 1-[4-(1-amino-2,2,2-trifl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
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Date in BDB:
3/10/2021
Entry Details
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