BDBM450381 2-cyclohexyl-N-[2,6-dichloro-4-(1,1,1-trifluoro-2-hydroxy-2-propanyl) phenyl]acetamide::US10676438, Example 50

SMILES CC(O)(c1cc(Cl)c(NC(=O)CC2CCCCC2)c(Cl)c1)C(F)(F)F

InChI Key InChIKey=ZAGKILKOITVECB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450381   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM450381(US10676438, Example 50 | 2-cyclohexyl-N-[2,6-dichl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
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Date in BDB:
3/10/2021
Entry Details
Go to US Patent