BDBM450378 1-{2,6-dichloro-4-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]phenyl}-3-{[2-(trifluoromethyl)-1,3-thiazole-5-yl]methyl}urea::US10676438, Example 33

SMILES O[C@H](c1cc(Cl)c(NC(=O)NCc2cnc(s2)C(F)(F)F)c(Cl)c1)C(F)(F)F

InChI Key InChIKey=FYKIECZTVKTYET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450378   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM450378(US10676438, Example 33 | 1-{2,6-dichloro-4-[(1R)-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
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Date in BDB:
3/10/2021
Entry Details
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