BDBM449854 5-[3-[(1R)-2-methoxy-1-methyl-ethyl]-2-methyl-benzimidazol-5-yl]-1,3-dimethyl pyridin-2-one ::US10703740, Compound 11::US11365186, Compound 11

SMILES COC[C@@H](C)n1c(C)nc2ccc(cc12)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=OXUQRRHKXLEHOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449854   

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM449854(5-[3-[(1R)-2-methoxy-1-methyl-ethyl]-2-methyl-benz...)
Affinity DataIC50: 98nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Epigenetix

US Patent
LigandPNGBDBM449854(5-[3-[(1R)-2-methoxy-1-methyl-ethyl]-2-methyl-benz...)
Affinity DataIC50: 98nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent