BDBM449851 5-[3-(2-methoxyethyl)-2-methyl-benzimidazol-5-yl]-1,3-dimethylpyridin-2-one ::US10703740, Compound 8::US11365186, Compound 8

SMILES COCCn1c(C)nc2ccc(cc12)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=MJFXOPWXWDLQLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449851   

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM449851(5-[3-(2-methoxyethyl)-2-methyl-benzimidazol-5-yl]-...)
Affinity DataIC50: 210nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
Epigenetix

US Patent
LigandPNGBDBM449851(5-[3-(2-methoxyethyl)-2-methyl-benzimidazol-5-yl]-...)
Affinity DataIC50: 210nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent