BDBM449708 US10703733, Example 321::US10988451, Example 321::US11643400, Example 321

SMILES C[C@H]1C\C=C\[C@H](O)[C@@H]2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc34)COc3ccc(cc23)C(=O)N=[S@@](=O)(C1)NC(=O)N[C@H]1C[C@@H]1C(F)F

InChI Key InChIKey=PTHSQDFMFIQJRX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 449708   

LigandPNGBDBM449708(US10703733, Example 321 | US10988451, Example 321 ...)
Affinity DataIC50: 0.0370nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent

LigandPNGBDBM449708(US10703733, Example 321 | US10988451, Example 321 ...)
Affinity DataIC50: 0.0370nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

LigandPNGBDBM449708(US10703733, Example 321 | US10988451, Example 321 ...)
Affinity DataIC50: 0.0370nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
Go to US Patent