BDBM449686 US10703733, Example 299::US10988451, Example 298::US11643400, Example 299

SMILES CO[C@H]1CC[C@H](OC)[C@H](C)C[S@@](=O)(NC(=O)c2cn(C)nc2OC)=NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@@H]14)c3c2

InChI Key InChIKey=LSTPFLXDLMKKNO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 449686   

LigandPNGBDBM449686(US10703733, Example 299 | US10988451, Example 298 ...)
Affinity DataIC50: 0.0390nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent

LigandPNGBDBM449686(US10703733, Example 299 | US10988451, Example 298 ...)
Affinity DataIC50: 0.0160nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

LigandPNGBDBM449686(US10703733, Example 299 | US10988451, Example 298 ...)
Affinity DataIC50: 0.0390nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
Go to US Patent