BDBM4494 (2,4-Dichlorophenyl)(6,7-dimethoxyquinolin-4-yl)-amine::6,7-Dimethoxyquinoline deriv. 6::N-(2,4-dichlorophenyl)-6,7-dimethoxyquinolin-4-amine::quinazoline deriv. 4a

SMILES COc1cc2nccc(Nc3ccc(Cl)cc3Cl)c2cc1OC

InChI Key InChIKey=AMKPAGTWVTZQPM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4494   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4494(quinazoline deriv. 4a | (2,4-Dichlorophenyl)(6,7-d...)
Affinity DataIC50: 84nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4494(quinazoline deriv. 4a | (2,4-Dichlorophenyl)(6,7-d...)
Affinity DataIC50: 84nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed