BDBM448584 US10696655, Example 55::US11168070, Example 55

SMILES CNC(=O)c1cn(C)c2ccc(N3CCCc4cc(-c5cnn(C)c5)c(cc34)C(F)F)c(F)c12

InChI Key InChIKey=ZEFMIQSSQVUAEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448584   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM448584(US10696655, Example 55 | US11168070, Example 55)
Affinity DataIC50: 4nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM448584(US10696655, Example 55 | US11168070, Example 55)
Affinity DataIC50: 4nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent