BDBM448570 US10696655, Example 42::US11168070, Example 42

SMILES CNc1cc(cc2n(C)c(=O)n(C)c12)N1CCCc2cc(-c3cnn(C)c3)c(cc12)C(F)F

InChI Key InChIKey=BHVQTHPCZNCHET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448570   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM448570(US10696655, Example 42 | US11168070, Example 42)
Affinity DataIC50: 19nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM448570(US10696655, Example 42 | US11168070, Example 42)
Affinity DataIC50: 19nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent