BDBM448420 1-[(6-{5-Azaspiro[2.4]heptan-5-yl]-2-methylpyridin-3-yl)methyl]-N-[(6R)-3-methyl-2H,4H,5H,6H-::US10695334, Example 45

SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CCC3(CC3)C2)c1

InChI Key InChIKey=GGNSSTSCYLPUKG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448420   

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448420(US10695334, Example 45 | 1-[(6-{5-Azaspiro[2.4]hep...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2021
Entry Details
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