BDBM448418 1-[(2-{3-Azabicyclo[3.1.0]hexan-3-yl}-4-methyl-::US10695334, Example 25

SMILES Cc1n[nH]c2[C@@H](CCc12)NC(=O)c1cn(Cc2cnc(nc2C)N2CC3CC3C2)nc1C

InChI Key InChIKey=YENZYVHIXPNVPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448418   

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448418(US10695334, Example 25 | 1-[(2-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2021
Entry Details
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