BDBM448094 US10689395, Compound ll::US11267820, Compound ll

SMILES CCNC(=O)CC1OC(c2c(cnn2C)-c2cn(C)c(=O)cc12)c1ccc(Cl)cc1

InChI Key InChIKey=FXXASPQDQMDKLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448094   

TargetBromodomain-containing protein 4(Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448094(US10689395, Compound ll | US11267820, Compound ll)
Affinity DataIC50: 1nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4(Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448094(US10689395, Compound ll | US11267820, Compound ll)
Affinity DataIC50: 1nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
Go to US Patent