BDBM448082 US10689395, Compound h::US11267820, Compound h

SMILES Cc1sc-2c(c1C)C(=NC(CC(=O)Nc1ccc(O)cc1)c1cc(=O)n(C)cc-21)c1ccc(Cl)cc1

InChI Key InChIKey=RWAXNILWBXRPAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448082   

TargetBromodomain-containing protein 4(Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448082(US10689395, Compound h | US11267820, Compound h)
Affinity DataIC50: 33nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4(Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448082(US10689395, Compound h | US11267820, Compound h)
Affinity DataIC50: 33nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
Go to US Patent