BDBM447739 US10689367, Example 58.0

SMILES CC(C)O[C@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cncc(C)c2)n1C1(C)CC1)c1ncc(C)cn1

InChI Key InChIKey=HTEUKMYHGCHQLZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 447739   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM447739(US10689367, Example 58.0)
Affinity DataEC50:  42nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent