BDBM447738 US10689367, Example 57.0

SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1CCS(C)(=O)=O)c1ncc(Cl)cn1

InChI Key InChIKey=HVOKXLJQHYYQJV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 447738   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM447738(US10689367, Example 57.0)
Affinity DataEC50:  211nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent