BDBM446702 US10689327, Compound (II)-3

SMILES CCCO[C@@H]1C[C@@H]2[C@@H]([C@@]2(F)C(O)=O)[C@]1(NC(=O)OCC=C)C(O)=O

InChI Key InChIKey=JBMRVZCRORVBOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 446702   

TargetMetabotropic glutamate receptor 2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM446702(US10689327, Compound (II)-3)
Affinity DataIC50: 75.1nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 3(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM446702(US10689327, Compound (II)-3)
Affinity DataIC50: 321nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent