BDBM4466 4-(3-Chloro-4-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile Hydrochloride::4-[(3-chloro-4-methylphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 29

SMILES COc1cc2ncc(C#N)c(Nc3ccc(C)c(Cl)c3)c2cc1OC

InChI Key InChIKey=OSNTXNDDUYHOPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4466   

TargetEpidermal growth factor receptor(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM4466(4-[(3-chloro-4-methylphenyl)amino]-6,7-dimethoxyqu...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM4466(4-[(3-chloro-4-methylphenyl)amino]-6,7-dimethoxyqu...)
Affinity DataIC50: 1.48E+3nMAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed