BDBM446589 CHEM-US-00102::US10669285, Example 39

SMILES Cc1cc(OC(F)(F)F)ccc1COC(=O)N1CCc2cc(nn2CC1)C(=O)N1CCc2[nH]nnc2C1

InChI Key InChIKey=URODJCVEOVWPIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446589   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM446589(CHEM-US-00102 | US10669285, Example 39)
Affinity DataIC50: 14nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
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