BDBM446581 CHEM-US-00094::US10669285, Example 31

SMILES FC(F)Oc1ccc(COC(=O)N2CCc3cc(nn3CC2)C(=O)N2CCc3[nH]nnc3C2)cc1F

InChI Key InChIKey=PRWLPVCFKAAQDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446581   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM446581(CHEM-US-00094 | US10669285, Example 31)
Affinity DataIC50: 22nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent