BDBM446244 US10669268, Example 15.39

SMILES Fc1cc(OC(F)(F)F)ccc1\C=C\C(=O)N1CC[C@@H]2CN(C[C@@H]2CC1)C(=O)c1ccc2[nH]nnc2c1

InChI Key InChIKey=JDGXFSOXRRFNCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446244   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM446244(US10669268, Example 15.39)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent