BDBM445778 US10669240, Compound 74

SMILES O=C(Nc1ccncc1NC(=O)c1n[nH]c2ccc(cc12)-c1cncc(CN2CCCCC2)c1)C1CC1

InChI Key InChIKey=DLBLWFYPWSQYDL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445778   

TargetProto-oncogene Wnt-1(Human)
Samumed

US Patent
LigandPNGBDBM445778(US10669240, Compound 74)
Affinity DataIC50: 120nMAssay Description:Reporter cell lines were generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
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TargetPulmonary surfactant-associated protein A1(Human)
Samumed

US Patent
LigandPNGBDBM445778(US10669240, Compound 74)
Affinity DataIC50: 2.74E+3nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 8-point dose-response curves f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent