BDBM445690 Ex. 26/KM-06-114/(I-26)::US10683309, Example 26::US11028104, Example 26
SMILES CCn1c2nc(Cc3cn4cc(C)sc4n3)n(Cc3ccc(F)cc3)c2c(=O)[nH]c1=O
InChI Key InChIKey=SMDQFUGCZCQACS-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 445690
Affinity DataIC50: 217nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
Affinity DataIC50: 217nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant MBP-tagged full length human THP2 using L-Trp as substrate assessed as formation of 5-HTP by measuring fluorescent propertyMore data for this Ligand-Target Pair