BDBM44544 2-(4-methoxyphenyl)ethyl-[3-(4-methoxyphenyl)-1-methyl-propyl]amine::4-(4-methoxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]-2-butanamine::4-(4-methoxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]butan-2-amine::MLS000532942::SMR000140380::US11999676, Compound 33::cid_2846243

SMILES COc1ccc(CCNC(C)CCc2ccc(OC)cc2)cc1

InChI Key InChIKey=CVNUMLMIVJNQST-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 44544   

TargetProtein Rev [8-24](Human immunodeficiency virus type 1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM44544(4-(4-methoxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]bu...)
Affinity DataIC50: 7.94E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay
TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM44544(4-(4-methoxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]bu...)
Affinity DataKi:  60nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM44544(4-(4-methoxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]bu...)
Affinity DataKi:  1.50E+3nMAssay Description:Synaptic vesicles were prepared from rat brain using a modification of a previously described procedure (Teng et al., 1998). Briefly, fresh whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent