BDBM445206 (S)-1-cyano-N-(4-(3-(methoxymethyl)phenyl)thiazol-2-yl)-N-methylpyrrolidine-2-carboxamide::US10669234, Example 145::US11319287, Example 145

SMILES COCc1cccc(c1)-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N

InChI Key InChIKey=ITEZYZUQTSNQSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445206   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM445206(US10669234, Example 145 | (S)-1-cyano-N-(4-(3-(met...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM445206(US10669234, Example 145 | (S)-1-cyano-N-(4-(3-(met...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent