BDBM445194 (S)-2-(5-(3-nitrophenyl)- isoindoline-2-carbonyl)- pyrrolidine-1-carbonitrile::US10669234, Example 133::US11319287, Example 133

SMILES [O-][N+](=O)c1cccc(c1)-c1ccc2CN(Cc2c1)C(=O)[C@@H]1CCCN1C#N

InChI Key InChIKey=GFCNPYUHBGCNDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445194   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM445194(US10669234, Example 133 | (S)-2-(5-(3-nitrophenyl)...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM445194(US10669234, Example 133 | (S)-2-(5-(3-nitrophenyl)...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent