BDBM445160 (S)-2-(4-(1H-pyrrolo[2,3-b]- pyridin-4-yl)indoline-1- carbonyl)pyrrolidine-1- carbonitrile::US10669234, Example 117::US11319287, Example 117

SMILES O=C([C@@H]1CCCN1C#N)N1CCc2c1cccc2-c1ccnc2[nH]ccc12

InChI Key InChIKey=CRINRUDDKSBHIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445160   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM445160(US10669234, Example 117 | (S)-2-(4-(1H-pyrrolo[2,3...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM445160(US10669234, Example 117 | (S)-2-(4-(1H-pyrrolo[2,3...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
Go to US Patent