BDBM445062 US10669227, Compound 6

SMILES COc1cc(\C=C\C(=O)C(C(=O)Nc2ccccc2)C(=O)\C=C\c2ccc(O)c(CO)c2)ccc1O

InChI Key InChIKey=FEVAWZWCLYKVLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445062   

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM445062(US10669227, Compound 6)
Affinity DataIC50: 8.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM445062(US10669227, Compound 6)
Affinity DataIC50: 1.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent