BDBM445061 US10669227, Compound 3

SMILES OCC(=O)C(C(=O)\C=C\c1ccc(O)cc1)C(=O)\C=C\c1ccc(O)cc1

InChI Key InChIKey=INOCVMCIBUBQTR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445061   

TargetMatrix metalloproteinase-9(Human)
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM445061(US10669227, Compound 3)
Affinity DataIC50: 6.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM445061(US10669227, Compound 3)
Affinity DataIC50: 7.00E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM445061(US10669227, Compound 3)
Affinity DataIC50: 8.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent