BDBM445060 US10669227, Compound 4

SMILES CNCc1ccc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)cc1

InChI Key InChIKey=GNTIMKCZICZFOB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445060   

TargetMatrix metalloproteinase-9(Human)
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM445060(US10669227, Compound 4)
Affinity DataIC50: 1.70E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

Target72 kDa type IV collagenase(Human)
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM445060(US10669227, Compound 4)
Affinity DataIC50: 2.50E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetCollagenase 3(Human)
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM445060(US10669227, Compound 4)
Affinity DataIC50: 2.50E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent