BDBM444970 Methyl (2-chloro-5-methoxy-3′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)(5-(N-(isoxazol-3-yl)sulfamoyl)pyridine-2-yl)carbamate::US10668067, Example 6

SMILES COC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1ccon1)c1cc(Cl)c(cc1OC)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=PFJJUJBDSFKUPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444970   

LigandPNGBDBM444970(Methyl (2-chloro-5-methoxy-3′-(trifluorometh...)
Affinity DataIC50: 167nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

LigandPNGBDBM444970(Methyl (2-chloro-5-methoxy-3′-(trifluorometh...)
Affinity DataIC50: 167nMAssay Description:Inhibition of human Nav1.7 by PatchXpress assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed