BDBM444965 6-((1-(2-chloro-5-methoxy-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-::US10668067, Example 5.1

SMILES COc1cc(c(Cl)cc1N(C(N)=O)c1ccc(cn1)S(=O)(=O)Nc1ccon1)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=CBQUOABWGSJKLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444965   

LigandPNGBDBM444965(6-((1-(2-chloro-5-methoxy-3'-(trifluoromethyl)-[1,...)
Affinity DataIC50: 7nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

LigandPNGBDBM444965(6-((1-(2-chloro-5-methoxy-3'-(trifluoromethyl)-[1,...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human Nav1.7 by PatchXpress assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed