BDBM444930 6-((3′-chloro-2,4′-difluoro-5-methoxy-4-biphenylyl)(methylcarbamoyl)amino)-N-2-pyrimidinyl-3-pyridinesulfonamide::US10668067, Example 2-1

SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1ncccn1)c1cc(F)c(cc1OC)-c1ccc(F)c(Cl)c1

InChI Key InChIKey=GLRZYYBPZLRWPR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444930   

LigandPNGBDBM444930(6-((3′-chloro-2,4′-difluoro-5-methoxy-...)
Affinity DataIC50: 18nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent