BDBM444921 6-((2-fluoro-3',5-dimethoxy-5'-(trifluoromethyl)-4-::US10668067, Example 1-82

SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1ncccn1)c1cc(F)c(cc1OC)-c1cc(OC)cc(c1)C(F)(F)F

InChI Key InChIKey=KKFNUCTWFLRSBI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444921   

TargetSodium channel protein type 9 subunit alpha(Human)
Amgen

US Patent

LigandBDBM444921(6-((2-fluoro-3',5-dimethoxy-5'-(trifluoromethyl)-4...)Copy SMILESCopy InChI

Affinity DataIC50: 18nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/15/2021
Entry Details
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