BDBM444865 6-((2,4'-difluoro-5-methoxy-3'-(trifluoromethyl)-4-::US10668067, Example 1-26

SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1ccon1)c1cc(F)c(cc1OC)-c1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=LELDAVTVXYDREA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444865   

TargetSodium channel protein type 9 subunit alpha(Human)
Amgen

US Patent

LigandBDBM444865(6-((2,4'-difluoro-5-methoxy-3'-(trifluoromethyl)-4...)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/15/2021
Entry Details
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