BDBM444831 2-(((1s,4s)-4-(((4- fluorophenyl)(phenyl) carbamoyloxy)methyl) cyclohexyl)methoxy)acetic acid::US10668033, Compound 35

SMILES OC(=O)COC[C@H]1CC[C@@H](COC(=O)N(c2ccccc2)c2ccc(F)cc2)CC1

InChI Key InChIKey=XCIVGPGSJPAWCB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444831   

TargetProstacyclin receptor(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM444831(2-(((1s,4s)-4-(((4- fluorophenyl)(phenyl) carbamoy...)
Affinity DataEC50:  56.9nMAssay Description:Compounds were screened for agonists of the human prostacyclin (PGI2) receptor using the HTRF assay for direct cAMP measurement (Gabriel et al., ASSA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
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