BDBM4442 4-(3-Bromophenylamino)-6,7-dimethoxyquinoline-3-carboxylic Acid Ethyl Ester::4-Anilino-6,7-dialkoxyquinoline deriv. 5::ethyl 4-[(3-bromophenyl)amino]-6,7-dimethoxyquinoline-3-carboxylate

SMILES CCOC(=O)c1cnc2cc(OC)c(OC)cc2c1Nc1cccc(Br)c1

InChI Key InChIKey=JTCMPRGLTUXNFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4442   

TargetEpidermal growth factor receptor(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4442(ethyl 4-[(3-bromophenyl)amino]-6,7-dimethoxyquinol...)
Affinity DataIC50: 8.13E+4nMpH: 7.4 T: 2°CAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed