BDBM443396 1-(2,4-dihydropyrazolo[4',3':4,5]pyrano[2,3-b]pyridin-7-yl)-3-(3-methoxybenzyl)urea::US10654860, Example 5

SMILES COc1cccc(CNC(=O)Nc2ccc3-c4c[nH]nc4COc3n2)c1

InChI Key InChIKey=WIJXPHURGMTOSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 443396   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM443396(US10654860, Example 5 | 1-(2,4-dihydropyrazolo[4',...)
Affinity DataIC50: 55nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL, assay containing 20 mM HEPES, pH 7.5, 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
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