BDBM443395 (R)-2-amino-N-(4,5-dihydro-2H-benzo[e]indazol-7-yl)-4-phenylbutan amid e::US10654860, Example 4

SMILES N[C@H](CCc1ccccc1)C(=O)Nc1ccc2-c3c[nH]nc3CCc2c1

InChI Key InChIKey=WZLUQVXPCAUXEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 443395   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM443395(US10654860, Example 4 | (R)-2-amino-N-(4,5-dihydro...)
Affinity DataIC50: 10nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL, assay containing 20 mM HEPES, pH 7.5, 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
Go to US Patent