BDBM443363 7-(1-Methyl-1H-indazol- 4-yl)-2-oxo-1,2- dihydrospiro[pyrido [2,3-b][1,4]oxazine- 3,3'-pyrrolidine]-1'- carbonitrile::US10654853, Example 136

SMILES Cn1ncc2c(cccc12)-c1cnc2OC3(CCN(C3)C#N)C(=O)Nc2c1

InChI Key InChIKey=QJGVWJHPIXHZOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 443363   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443363(US10654853, Example 136 | 7-(1-Methyl-1H-indazol- ...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
Go to US Patent