BDBM442790 N-{1-[3-Fluoro-4-(trifluoromethyl)phenyl]cyclopropyl}-5-methylpyrazolo[1,5-a]pyrimidin-7-amine::US10647727, Example 47

SMILES Cc1cc(NC2(CC2)c2ccc(c(F)c2)C(F)(F)F)n2nccc2n1

InChI Key InChIKey=UFWUWKLBEHSXFL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442790   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM442790(US10647727, Example 47 | N-{1-[3-Fluoro-4-(trifluo...)
Affinity DataKi:  199nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent